Molecular Genetics Laboratory
Publications
- Mutations in the novel gene Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse. Odeh H, Hunker KL, Zheng L, Peters LM, Gagnon L, Hagiwara N, Skynner M, Brilliant MH, Allen N, Morell RJ, Johnson KR, Raphael Y, Bartles JR, Belyantseva IA, Friedman TB, and Kohrman DC. (under review July 2006, Nature Genetics)
- Age-associated Changes in Cochlear Gene Expression in Normal and Shaker 2 Mice. Gong TWL, Karolyi JI, MacDonald J, Beyer L, Raphael Y, Kohrman DC, Camper SA, and Lomax MI. (accepted May 2006, J. Assoc. Res. Otolarng.)
- Odeh H, Hagiwara N, Skynner M, Mitchem KL, Beyer LA, Allen N, Brilliant M, Lebart MC, Dolan DF, Raphael Y, and Kohrman DC: Characterization of two transgene insertional mutations at pirouette, a mouse deafness locus. Audiol. Neurootol. 9:303-314, 2004.
- Karolyi IJ, Probst FJ, Beyer LA, Odeh H, Dootz G, Cha KB, Martin D, Avraham KB, Kohrman DC, Dolan DF, Raphael Y, Camper SA: Myo15 function is distinct from Myo6, Myo7a, and pirouette genes in development of cochlear stereocilia. Hum. Mol. Genet. 12:2797-2805, 2003.
- Naz S, Giguere CM, Kohrman DC, Mitchem KL, Riazuddin S, Morell RJ, Ramesh A, Srisailpathy S, Deshmukh D, Riazuddin S, Griffith AJ, Friedman TB, Smith RJH, Wilcox ER: Mutations in a novel gene TMIE are associated with hearing loss at the DFNB6 locus. American Journal of Human Genetics 71:632-636, 2002.
- Mitchem KL, Hibbard E, Beyer LA, Bosom K, Dootz GA, Dolan DF, Johnson KR, Raphael Y, Kohrman DC: Mutation of Tmie, a gene encoding a predicted integral membrane protein, results in stereocilia defects in the mouse deafness mutant spinner. Hum. Mol. Genet., 11:1887-1898, 2002.
- Beyer LA, Odeh H, Probst FJ, Lambert EH, Dolan DF, Camper SA, Kohrman DC, Raphael Y: Hair cells in the inner ear of the pirouette and shaker 2 mutant mice. J. Neurocyt. 29:227-239, 2000
