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Kresge Hearing Research Institute

Department of Otolaryngology

Fluorescent micrograph of labeling produced by Fluororuby delivered from an Alzet mini-pump via a silicon drug-delivery probe implanted in visual cortex for 7 days

Neurophysiology Menu

Neuropharmacology/Physiology Laboratory

Sanford C. Bledsoe, Jr., Ph.D., Laboratory Director

With the retirement of Dr. Bledsoe, the research program of the Neuropharmacology/Physiology Laboratory has been significantly reduced. Formerly, the research focused on four programs designed to:

  1. develop acute and chronic micromachined drug-delivery systems,
  2. determine the role that descending (efferent) neural pathways play in cochlear function and central acoustic processing,
  3. understand mechanisms of brain adaptability that occur with deafness, and
  4. elucidate the characteristics of central auditory system activation associated with cochlear prosthetic stimulation.

In retirement, Dr. Bledsoe will continue active collaborations with Drs. Altschuler, Anderson, Holt, Le Prell, Pfingst, Raphael, and Shore on studies related to lateral olivocochlear efferents, central auditory prostheses, and tinnitus.